Longevity : EI Weekend 3428
On longevity. How AI & other tech is helping fuel what could be a vast upswing in both lifespan and Healthspan.
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MACRO THOUGHTS
According to the World Health Organisation (WHO), the global average life expectancy for a woman is 74 years and 68.9 for a man nowadays.
In 2024, there were a total of 722,000 centenarians among a global population of 8.2 billion.
Some fascinating developments, partly fuelled by AI and other modern technological marvels, show that — presuming the ‘bots don’t kill us all — the world record 122.45 years (122y, 164 days) of France’s Jeanne Calmont (1875–1997) could become the new norm within the next few decades.
Provided (a big ‘if’ naturally) telomeres and natural markers of aging can be better managed then it’s plausible to expect that within 20–30 years we can see humans not only enjoying a lifespan to 120 years but even enjoying a “healthspan” which means 120 ‘good’ years.
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“Confessions of A Carbon Hunter”
Guest: Dr Richard Sandor
November 18th, 2025
1600 UK, 1700 CET, 1200 EST
Professor Richard Sandor is the #OG of financial #ETD. He invented financial futures and environmental markets…which is only a part of his incredible legacy.
Join our discussion from the AFM Tech Day as Patrick L Young is honoured to host a fireside chat with “THE Doc.”
IN BIGWORLD
Perhaps unsurprisingly, as we all know testosterone-driven bravado cum risk management tends to get in the way of male longevity, men live shorter lives than women.
However it’s also striking to note at the ‘long end of the curve’ that the top 10 oldest women ever all lived longer than the oldest man.
Jeanne Calmont of France continues to top the longevity table at 122 years, 164 days while in tenth place is Chiyo Mitako of Japan died at 117 years, 81 days in 2018.
By comparison, Japan’s Jiroemon Kimura who passed away in 2013 remains the world’s oldest man at 116 years and 54 days.
Ranked: The World’s Oldest People In History
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BITCARNAGE
Stable?
If you don’t read anything else, just read this Speech By Governor Miran On Stablecoins And Monetary Policy (Federal Reserve Board). A central banker’s lament on what may or may not be the future of “stablecoins” and a fair appraisal of what could yet go horribly wrong.
If you enjoyed this excerpt you may be interested to know that you can read Bitcarnage every day in Exchange Invest.
Alternatively, if you want to follow Bitcarnage — the daily update on happenings in the world of crypto and digital assets, then you can find Bitcarnage as a standalone on Substack.
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& ATHEX Gets A Deal Tweak
OF INTEREST
As always, a review of interesting reading to provoke thoughts and consideration… Not sure we agree with much of it….but it’s thought-provoking!
10 Most Important Discoveries About Human Longevity
Science News Today
A4M Longevity Watchlist: Defining Advances And 4 Trends Worth Your Attention
WorldHealth
Longevity Science: How Anti-Aging Medicine Is Advancing
Business Bofa
Advances In Longevity Research
Slowing The Clock
The Longevity Revolution: Biotech Trends Extending Healthspan In 2025
Tyler D Brown, PhD
Bridging Expectations And Science: A Roadmap For The Future Of Longevity Interventions
PMC
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“Face Your Financial Fears”
Guest: Jake Cousineau
November 11th, 2025
1600 UK, 1700 CET, 1200 EST
Jake Cousineau invites us to “Face Your Financial Fears” based on the wealth of information in his latest book.
FINANCE BOOK OF THE WEEK
“The Rich in Public Opinion: What We Think When We Think about Wealth” by Rainer Zitelmann examines how we think about a minority that, while undeniably powerful, can still be the subject of scapegoating — often with dire effects for us all.
Get the book here.
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Suggestions welcome if you would like to nominate a book for us to cover!
Our next Book of the week will be unveiled Saturday in the EI Weekend Edition.
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CAPITAL MARKET REVOLUTION
First published in 1999, “Capital Market Revolution!” offered a clear, concise roadmap for navigating the financial revolution fueled by technology. And 25 years later, as the world of fintech continues to evolve, the core principles laid out in the book remain surprisingly sharp
This new edition was produced to celebrate PLY ringing the NYSE Closing Bell July 5th, 2024. There are several new sections of PLY pith to add 10,000 more words of context and the original book which is remarkably prescient and elegantly dated all at once! It’s only $9.99 on Kindle, a fraction of the original price in 1999 to encourage revolutionaries with any budget!
Get the book here.
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LAST WORD
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The shift from lifespan to healthspan is crucial. Reaching 120 years only matters if those are functional years. The telomere managment research you mention could be transformative, but we also need paralel advances in cognitive preservation and metabolic health to make extended longevity meaningful rather than just prolonged decline.